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Lancet Oncology

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Crowdsourcing a Better Prostate Cancer Prediction Tool

Press Release | University of Colorado Anschutz Medical Campus | November 15, 2016

Knowing the likely course of cancer can influence treatment decisions. Now a new prediction model published today in Lancet Oncology offers a more accurate prognosis for a patient's metastatic castration-resistant prostate cancer. The approach was as novel as the result - while researchers commonly work in small groups, intentionally isolating their data, the current study embraces the call in Joe Biden's "Cancer Moonshot" to open their question and their data, collecting previously published clinical trial data and calling for worldwide collaboration to evaluate its predictive power...

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First-Ever Crowdsourced Prostate Cancer Data-Mining Competition Discovery Impacts and Predicts Patient Survival

Press Release | Project Data Sphere, Sage Bionetworks, FIMM | November 16, 2016

Today, a breakthrough report in the international journal Lancet Oncology demonstrates how a collaborative effort to analyze broadly accessible clinical data led to novel insights and improvements in cancer treatment and management. Participants in the Prostate Cancer DREAM (Dialogue for Reverse Engineering Assessments and Methods) Challenge – an effort initiated by Project Data Sphere, LLC (PDS) in collaboration with Sage Bionetworks using proven DREAM methodology – developed new risk factor models for metastatic castration-resistant prostate cancer (mCRPC)...

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