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Antibiotic Resistance Doesn't Just Make Bacteria Harder To Kill – It Can Actually Make Them Stronger

By Gerald Pier, Harvard Medical School , and David Skurnik, Harvard Medical School | September 10, 2015

Bacteria can become drug-resistant in two ways – resistance can be natural, meaning that the genes conferring resistance are already present in the bacterial chromosome, or they can be acquired through mutation or by picking up antibiotic-resistance genes from other microbes. It is now possible to use new DNA-sequencing technologies to take a closer look at how the antibiotic resistance can make some bacteria weaker or stronger. And in a new study, we found that – contrary to conventional wisdom around antibiotics – resistance can actually make some bacteria fitter and even more virulent.

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Promising Antibiotic Discovered In Microbial "Dark Matter"

Heidi Ledford | Scientific American | January 7, 2015

Potential drug kills pathogens such as MRSA—and was discovered by mining "unculturable" bacteria...

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