NIH Common Fund

See the following -

New Imaging Technique Overturns Longstanding Textbook Model of DNA Folding

Press Release | National Institutes of Health | July 27, 2017

How can six and half feet of DNA be folded into the tiny nucleus of a cell? Researchers funded by the National Institutes of Health have developed a new imaging method that visualizes a very different DNA structure, featuring small folds of DNA in close proximity. The study reveals that the DNA-protein structure, known as chromatin, is a much more diverse and flexible chain than previously thought. This provides exciting new insights into how chromatin directs a nimbler interaction between different genes to regulate gene expression, and provides a mechanism for chemical modifications of DNA to be maintained as cells divide...

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Open Science Prize Announces Epidemic Tracking Tool as Grand Prize Winner

Press Release | Open Science Prize, Wellcome, Howard Hughes Medical Institute , National Institutes of Health | February 28, 2017

A prototype online platform that uses real-time visualization and viral genome data to track the spread of global pathogens such as Zika and Ebola is the grand prize winner of the Open Science Prize. The international team competition is an initiative by the National Institutes of Health, in collaboration with the Wellcome Trust and the Howard Hughes Medical Institute (HHMI). The winning team, Real-time Evolutionary Tracking for Pathogen Surveillance and Epidemiological Investigation, created its nextstrain.org prototype to pool data from researchers across the globe, perform rapid phylogenetic analysis, and post the results on the platform’s website...

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