Open Medicine
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Sage Bionetworks Advocates for Open Systems in Health Research
Sage Bionetworks, a nonprofit biomedical research organization, continues its work to redefine the way in which health data is gathered, shared and used through the use of open systems, incentives and norms. In a Nature commentary published today, a set of governing principles for digital health data analysis that are designed to maximize the contribution of large-scale digital data to advancing medical care are described. This commentary was co-authored by John Wilbanks, Chief Commons Officer at Sage Bionetworks and Eric Topol, MD, Director of the Scripps Translational Science Institute, and Chief Academic Officer of Scripps Health. The two work together on the NIH-funded Precision Medicine Initiative that was announced earlier this month.
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Scientists Launch Open Source Computational Platform to Study Biological Processes
Agent-based simulations (ABS) are powerful computational tools that help scientists understand complex biological systems. These simulations are an inexpensive and efficient way to quickly test hypotheses about the physiology of cellular tissues, organs, or entire organisms. However, many ABS do not take full advantage of available computational power, and the majority of ABS platforms on the market are designed with a particular use case in mind.
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The Collateral Benefits of India's Open Source Drug Discovery Programme
India's Open Source Drug Discovery programme is struggling for lack of expertise and a research ecosystem. However, the programme's real contribution may be the creation of just such an ecosystem Read More »
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The Evolving Role of Open Source Software in Medicine and Health Services
In this article, we highlight the barriers to progress and discuss the dangers of pursuing a standardization framework devoid of empirical testing and iterative development. We give the example of the openEHR Foundation, which was established at University College London (UCL) in London, England, with members in 80 countries....We argue that such an approach is now essential to support good discipline, innovation, and governance at the heart of medicine and health services, in line with the new mandate for health commissioning in the United Kingdom's National Health Service (NHS), which emphasizes patient participation, innovation, transparency, and accountability. Read More »
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The Open Patient: Advocating for Open Access to Medical Data
Steven Keating had always been interested in data and learning about things, which is why he volunteered to do a research scan when he was a student. The scan revealed an abnormality. In 2014, the abnormality had grown into a massive tumor. Soon he learned that there were many barriers keeping him from accessing his own data. "And that's what I've been sharing, which is this question: How come as a patient we're last in line for our own data? How come my doctors and my university researchers can see my tumor genome and I can't?"
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Tracking Deadly Superbug Infections Across Europe with Web-Based Open Tools that Use Genome Sequencing and Open APIs
For the first time, scientists have shown that MRSA (methicillin-resistant Staphylococcus aureus) and other antibiotic-resistant ‘superbug’ infections can be tracked across Europe by combining whole-genome sequencing with a web-based system. In mBio today (5 May 2016) researchers at Imperial College London and the Wellcome Trust Sanger Institute worked with a European network representing doctors in 450 hospitals in 25 countries to successfully interpret and visualise the spread of drug-resistant MRSA...
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tranSMART Foundation i2b2 Symposium Announced for June 23 at Harvard Medical School
The tranSMART Foundation...today announced that it has joined forces with the Harvard Medical School (HMS) Department of Biomedical Informatics (DBMI) to host the tranSMART Foundation i2b2 (Informatics for Integrating Biology and the Bedside) Symposium on June 23, 2016 at HMS. The all-day meeting, beginning at 8:00 a.m. with registration and the program running from 8:30 a.m. -5:30 p.m., will focus on the integration between and use of the tranSMART platform for translational medicine and the i2b2 platform.
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Two Independent Sources of Medical and Mental Health Research Shut Down in Canada
The Canadian Women’s Health Network (CWHN), for two decades a major source of critical, independent research and information on women’s health and mental health, has had to stop all its activities and close its doors indefinitely after the Canadian government took away its funding...The announcement came only weeks after the independent Canadian open-access journal Open Medicine also was forced to shut down. Both blamed declining support for scientific research that does not serve corporate interests.
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Vanderbilt U Researchers Open Source Blueprints and Software for Focused Ultrasound System
Charles Caskey, Ph.D., and Will Grissom, Ph.D., at the university’s Institute of Imaging Science (VIIS) decided to address the technical difficulty of configuring focused ultrasound (FUS) equipment and the limited number of commercial machines available at present. "The lack of well-described, accessible, pre-clinical focused ultrasound systems limits progress and decreases repeatability of new developments,” Dr. Caskey told the Focused Ultrasound Foundation website. “Our open-source system can deliver repeatable, precise, and quantifiable thermal and mechanical focused ultrasound over an extended period in small animals.” Read More »
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tranSMART Foundation i2b2 Symposium
The tranSMART Foundation has joined forces with the Harvard Medical School (HMS) Department of Biomedical Informatics (DBMI) to host the tranSMART Foundation i2b2 (Informatics for Integrating Biology and the Bedside) Symposium on June 23, 2016 at HMS. The all-day meeting, beginning at 8:00 a.m. with registration and the program running from 8:30 a.m. -5:30 p.m., will focus on the integration between and use of the tranSMART platform for translational medicine and the i2b2 platform. The sessions will cover the use of tranSMART and i2b2 in research programs, as well as presentations by scientists and clinicians who are using both platforms in their research studies. Confirmed speakers include...
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openEHR and FHIR – Fiends or Foes? - HIGHmed Symposium 2021
Ever since the COVID-19 pandemic, the need for interoperable and scalable data infrastructures within healthcare has become even more apparent. National and regional governments address these challenges by introducing open platforms, a novel paradigm to enable the data flow required to harness the full potential of big data in medicine. To underline the importance of open platforms, and to provide examples of novel implementations to political stakeholders and the health IT community, we dedicate our this year’s HiGHmed Symposium to openEHR and FHIR, the underlying eHealth standards of the data environment of tomorrow.
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