The MycetOS (Mycetoma Open Source) project was launched today by the University of Sydney, Erasmus MC, and the Drugs for Neglected Diseases initiative (DNDi) to use an Open Pharma approach to discover compounds that could lead to new treatments for patients suffering from fungal mycetoma (eumycetoma), a devastating disease for which current treatments are ineffective, expensive, and toxic.
Open source drug discovery
See the following -
Advancing Antimalarial Drug Research Through Open Source Initiatives
Jeremy Burrows | The Guardian | July 24, 2013
Open research can lead to new drugs tackling diseases that afflict the world's poor. But first, more scientists need to buy into contributing to something bigger than their careers Read More »
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Africa: Partners Commit To Bolster Open Source Research
Press Release |
Medicines for Malaria Venture (MMV), Drugs for Neglected Diseases initiative (DNDi), Royal Society of Chemistry (RSC) |
November 27, 2013
The Royal Society of Chemistry (RSC), UK, Drugs for Neglected Diseases initiative (DNDi) and MMV have signed a memorandum of understanding (MoU) to collaborate in an effort to build a global community of researchers contributing to open source drug discovery for diseases of poverty. Read More »
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Can Open Science Help Patients And Save Pharma?
By Timothy King | June 22, 2014
Open science research and development hybrid development model can protect pharma company profits while reducing costs of medicines for consumers Read More »
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Heart Failure Breakthrough May Come From "Open Source" Cancer Drug Development: Discoveries
Brie Zeltner | Cleveland.com | August 19, 2013
A newly-discovered cancer drug may be a breakthrough in treating heart failure, thanks to a groundbreaking “open source” approach to drug discovery that allowed a Case Western Reserve University heart specialist free access to the compound for his research. Read More »
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International Team of Scientists Open Sources Search for Malaria Cure
By Alice Williamson | June 21, 2014
The Open Source Malaria (OSM) project operates along very similar lines to traditional medicinal chemistry projects in that the team is looking for an antimalarial drug candidate suitable for Phase 1 clinical trials. However, the day to day running of the project works quite differently and is probably most clearly defined by the team’s commitment to The Six Laws of Open Science... Read More »
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New Open Source Drug Discovery Project Aims to Develop Mycetoma Treatment
Press Release |
ErasmusMC , University of Sydney , DNDi |
February 6, 2018
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Open Source Malaria Research Paves Way for Inexpensive Medicines
Press Release |
University of Sydney |
September 14, 2016
A real-time drug discovery project involving some 50 researchers in nine countries has shown open source malaria research works - providing a potential alternative for medicines similar to the way in which open source products compete with proprietary products in software. Malaria is one of the leading causes of mortality in developing countries – last year killing more than 400,000 people. Researchers worldwide have found the solution for drug discovery could lie in open, “crowd-sourced” science...
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Patient Engagement, Data Liberation And Portability
Christine Årdal and John-Arne Røttingen | PLOS Neglected Tropical Diseases | September 20, 2012
Open source drug discovery can be an influential model for discovering and developing new medicines and diagnostics for neglected diseases. It offers the opportunity to accelerate the discovery progress while keeping expenditures to a minimum by encouraging incremental contributions from volunteer scientists.
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Reinventing Discovery On The Way To The Sage Congress
Matthew Todd | Intermolecular | April 18, 2013
I’m in San Francisco for the Sage Commons Congress, and am excited to be able to contribute. [...] To salvage the 13 hours I read Michael Nielsen’s Reinventing Discovery, finally. It’s testament to the quality of the writing that I glided through it in one sitting (I did have a window seat)... Read More »
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Transitioning To Open Systems In Drug Discovery
John Wilbanks | FasterCures | October 18, 2013
Bringing the ideas of “open source” into the pharmaceutical process is far from simple. It requires a careful understanding both of the realities of open source as a software development process well as the realities of therapy research, development, and regulatory approval. Read More »
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Why Open Source Isn't The Same As Free
Matthew Todd and Abdi Ismail | The Guardian | August 14, 2013
In this week's letters, the science lead at Open Source Malaria explains the semantics of collaborative drug discovery Read More »
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