Salk Institute
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New Imaging Technique Overturns Longstanding Textbook Model of DNA Folding
How can six and half feet of DNA be folded into the tiny nucleus of a cell? Researchers funded by the National Institutes of Health have developed a new imaging method that visualizes a very different DNA structure, featuring small folds of DNA in close proximity. The study reveals that the DNA-protein structure, known as chromatin, is a much more diverse and flexible chain than previously thought. This provides exciting new insights into how chromatin directs a nimbler interaction between different genes to regulate gene expression, and provides a mechanism for chemical modifications of DNA to be maintained as cells divide...
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Would Jonas Salk Join The Open-Source Movement?
...While Salk’s lasting impression on medicine and its place in society is obvious, his philosophy on the patent-free development of the polio vaccine — and its applicability to the increasing influence of technology on biological and biomedical research — is also an important part of what he left behind...
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